Sunday, December 29, 2019

Why It Is Still Considerate As The Gold Standard For Dna...

This technique is still very useful overall because of its low error range, and also is the reason why it is still considerate as the Gold standard for DNA sequencing, among other things to validate NGS data (Pareek Smoczynski 2011). Aiming to reduce costs and improve quality and efficiency, the New Generation Sequencers appeared. With the surging of NGS technologies, today it is viable to sequence in a particular subject with a suspected genetic disease or with tendency to that compound disease, up to thousands of genes at the same time (Pareek Smoczynski 2011). There are different existing methods, however all shared similar features about Massive Parallel sequencing reactions. All of them required a pre-determined library sample preparation through DNA break-up and amplification by custom adaptors. Each library fragment is amplified on a solid surface (cell flow) by covalent-attached DNA linkers (oligonucleotides) which hybridize the library adaptors. This amplification creates millions of DNA clusters, each originated from a single library fragment. Each fragment will act as a single sequencing reaction. After this, each machine provides a raw data at the end of the sequencing run. This run data is a collect ion of DNA sequences that were generated of each cluster. At the moment, the most broadly used targeted sequencing method is maybe the Whole Exome Sequencing (WES) since is the known genome protein-coding region and represents no more than 2% of the geneticShow MoreRelatedDeveloping Management Skills404131 Words   |  1617 Pages Editorial Director: Sally Yagan Editor in Chief: Eric Svendsen Acquisitions Editor: Kim Norbuta Editorial Project Manager: Claudia Fernandes Director of Marketing: Patrice Lumumba Jones Marketing Manager: Nikki Ayana Jones Senior Marketing Assistant: Ian Gold Senior Managing Editor: Judy Leale Senior Production Project Manager: Kelly Warsak Senior Operations Supervisor: Arnold Vila Operations Specialist: Ilene Kahn Senior Art Director: Janet Slowik Interior Design: Suzanne Duda and Michael Fruhbeis PermissionsRead MoreManagement Course: Mba−10 General Management215330 Words   |  862 PagesManaging Change 121 121 147 147 Text 3. Why Organizations Change Text Cohen †¢ Effective Behavior in Organizations, Seventh Edition 14. Initiating Change 174 174 Text iii Cases 221 221 225 The Consolidated Life Case: Caught Between Corporate Cultures Who’s in Charge? (The)(Jim)(Davis)(Case) Morin−Jarrell †¢ Driving Shareholder Value I. Valuation 229 229 253 279 1. The Value−Based Management Framework: An Overview 2. Why Value Value? 4. The Value Manager Harvard

Saturday, December 21, 2019

Abortion Should Not Be Legalized - 972 Words

Abortion is killing over 1.4 million unborn children in a year (â€Å"They’re Not†). For example, there was the case where a doctor got arrested for killing seven babies and a patient. The clinic he had was described as the house of horror by detectives because doctor Gosnell kept baby parts on a shelf in his clinic. In addition, it was said that he â€Å"forced the live birth of viable babies in the sixth, seventh, and eighth-month pregnancy and then killed those babies by cutting into the back of the neck with scissors and severing the baby’s spinal cord† (â€Å"Abortion Is† ). Even though people feel it is a women’s right to abort, abortion should not be legalized because it ends a human life, some women have psychological damage, and some women even die or have physical damage from having an abortion. In the early centuries, abortion was permitted and used by healers who performed them and taught other women how to do it (â€Å"History†). In the 1800’s, most abortions were illegal in the United States except those that were used to save a woman’s life (â€Å"History†). Also, it was a woman’s right to choose to abort or keep the child. In the mid-19th century, a humanitarian reform supported that abortion should be a crime (‘History†). Therefore, abortion became a crime and a sin for several reasons, one of them being cruelty. Abortion became a crime due to some of the following examples. The first reason why abortion should not be legalized is because it is killing a human life. SomeShow MoreRelatedShould Abortion Be Legalized?1357 Words   |  6 Pagessaid Margaret Sanger (Quotes About Abortion). An abortion is the deliberate termination of a human pregnancy, most often performed during the first 28 weeks of pregnancy. 69% of women that have abortions are economically disadvantaged (The Demographics Of Abortion: It s Not What You Think). This is one of the reasons abortions should stay legalized, over half of the women would have been struggling to take care of their child without it. Abortion was legalized on January 27, 1973 in a 7-2 decisionRead MoreShould Abortion Be Legalized?1495 Words   |  6 Pagesbetter, whom the president should be or who or if at all, we should be at war with; no one can unanimously agree on any topic in this country. This is no different then with the current hot topic of abortion. Abortion, although legal in this country, is still tr eated and viewed as taboo because of a dominantly Christian-American society. Some Christians make it seem that if you are pro-choice then you are pro-murder. However this is not the case. I will explain what abortion really is and why it isRead MoreShould Abortion Be Legalized?1172 Words   |  5 Pages Although some believe abortion is morally and ethically wrong should it be legal for victims of rape or incest who have no other alternative? Pro-Life advocates believe as horrible as abortion is, the baby is still innocent of any crime. Nobody should be killed for the crime of another person. While Pro-Choice advocates believe if a woman is pregnant by rape, compassion demands that she be allowed to abort. On the other hand, the pro-life vs pro-choice debate tends to overlook the fact that theRead MoreShould Abortion Be Legalized?869 Words   |  4 Pages Abortion has become a common argument topic in America; numerous individuals consider themselves pro-life and others pro-choice. Those who consider themselves pro-life oppose abortion, while those who are pro-choice advocate for abortion to be legalized. I believe that abortion should be illegal and that life should be recognized upon conception. Almost all abortions occur during the first trimester when the fetus cannot live outside of the mother’s body. People who are pro-choice believe thatRead MoreShould Abortion Be Legalized?1200 Words   |  5 PagesAbortion is a very hot topic that has been repeatedly contended over for the past few years. The argument is should abortion be legalized or not? First before we get into the many sides of abortion we must to know what is abortion. Abortion means ending a pregnancy before the fetus can live independently outside the world. If abortion happens unplanned before 24 weeks of pregnancy. It is called a miscarriage. Abortion is caused design to order to end the pregnancy (Brown, 2013). This can be completeRead MoreShould Abortion Be Legalized?1680 Words   |  7 Pagesrights. A hot topic that is one of the most refuted in today’s society is abortion. One may not see abortion to be acceptable, although, does it make it right to take away that right from someone el se? It has taken women a lot of fight and willpower to gain rights to their own bodies, illegalizing abortion would take that right away. Therefore, the question is, should abortion continue to be legalized? First and foremost, abortion can be seen as a way of having full control over one’s personal body.Read MoreAbortion Should Be Legalized Or Not?1902 Words   |  8 PagesDecember 2014 Abortion should be legalized or not? Abortion in itself is a very controversial topic and different people has different views on it some says it should be legalized while others in the other hand says legalization of abortion can create a lot of problems. Abortion is the spontaneous or induced termination of pregnancy before fetal viability. According to WHO, abortion is the pregnancy termination prior to 20 weeks gestation or a fetus born weighing less than 500 grams. Abortion may be self-induced;Read MoreShould Abortion Be Legalized?1685 Words   |  7 Pagesagainst women having an abortion, no matter what situation they are in, the point of women having their own rights should include whether they choose to have their own kid or not. The United States today is very divided on the whole abortion issue, typically republicans are against it calling theirselves â€Å"pro-lfe† and democrats are typically for abortion and they call theirselves â€Å"pro-choice.† Abortion had been practiced in the United States ever since 1880, but it wasn t legalized nationwide untilRead MoreShould Abortion Be Legalized?1799 Words   |  8 PagesAbortion across America Teenage pregnancy has become a norm in America. Sex education is gradually losing significance among the youth. Despite the wide range of contraceptives, many young women are continually getting pregnant. Additionally, the number of young boys and girls ruining their lives at an early stage as a result of quick moments of pleasure is alarming. Moreover, the advancement in technology is an increasingly contributing factor to the high rates of teenage pregnancy (GarfieldRead MoreAbortion Should Not Be Legalized1237 Words   |  5 PagesMany women in the world consider doing abortion, and this has been huge on-going controversial issues for a long time. The women in country X want to abort because they do not want their daughters to live restricted just like them, but it cannot be justified. Abortion should not be legalized because the woman’s body is not her own property that she has no right to control over the fetus, and it kills the innocent. According to Judith Thomson, abortion is permissible because women â€Å"are granting

Friday, December 13, 2019

Truman Capote Research Free Essays

Truman Capote was best known for his vivacious and eccentric way of life, as well as his works in the 20th Century. While reading his first novel ever printed by him, Other Voices, Other Rooms, the characters and story line that Capote created was one that would clearly strike a touching insolence to many readers. Not only does Capote fascinate readers with his life, but also with the heart of life and nostalgia that is created when reading any of his work. We will write a custom essay sample on Truman Capote Research or any similar topic only for you Order Now Capote’s writing career began very prematurely and increased throughout the years of his life. Once Capote finished school, he began writing for The New Yorker and eventually started writing short stories. At the age of seventeen, magazines published many of his stories, which eventually ended up leading to him writing his first novel. Capote ended up writing his first novel, Other Voices, Other Rooms, in 1948 and it brought almost instantaneous awareness and disgrace. Although it was not one of his most accepted novels, it without doubt got him on the right path. Truman Capote was born on September 30, 1924, where his life began in New Orleans, Louisiana, where he spent very little of his life (Jacob197). At the age of only four years old, Capote’s parents were divorced. Capote’s mother, Lillie Faulk, then left him to be raised by her family while she went to go become a star (Pimpton 7). Her family lived in Monroeville, Alabama, where Capote spent most of his life living amongst his aunts, uncles, cousins and his friends. People actually consider that when Truman’s mother neglected him, it was the establishment of their relationship in the future (Biography). Throughout his life, Capote grew up being influenced by many of his family members and other peers that bounded him in the small town of Monroeville. It wasn’t until 1933, that Capote’s mother intended to bring her son to come live with her and her new husband Joe Capote in Manhattan, New York. Capote abandoned the countryside life in Monroe and traded it in for a life in Manhattan with his mother. Joe Capote later on adopted Truman, and by 1935, he changed his name from Truman Streckfus Persons, to Truman Garcia Capote (Biography). In Capote’s later years, he went on to be a success. He lived a glamorous life. He enjoyed to party and never gave a care in the world. He entertained many of the elite people in the world and on August 25, 1984, Truman Capote died of liver disease at his old friend’s house in Los Angeles, California. Other Voices, Other Rooms is the piece work that he relates to most. In his own words, Capote says, â€Å"this symbolized my hunt for my own father, whom I hardly ever saw, and the fact that the man old man is crippled and mute was my way of conveying my own incapability to correspond with my father; I was not only the boy in the story but also the old man†(Pimpton80). It was recorded as public knowledge that Capote engulfed his stories with his own life experiences, but it was made incredibly apparent in this particular novel, with his expression and approach. One particular example would be the un-canny similarity of the main character Joel to Capote himself, â€Å"†¦too pretty, too delicate and fair-skinned†¦and a girlish tenderness softened his eyes†¦Ã¢â‚¬ (Capote4). Another method that Capote used a lot was his talent to describe a scene with incredible accuracy and portrayal, â€Å"A face shudder like a white stunning moth, smiled. She beckoned to him, shining and silver, and he knew he must go: unafraid, not hesitating, he paused only at the garden’s edge where, as though he’d forgotten something, he stopped and looked back at the bloomless, descending blue, at the boy he had left behind. † (Capote231). Throughout his novels, Capote uses these strong metaphors and descriptive language to show that his character, Joel, came to the house as one person and leaving as another. One with new experiences with life. Many people knew Truman Capote as a literary genius (Biography). His work was different yet satisfying. Many of his characters are memorable, along with the places they lived and explored. Capote put us in his world and a large amount of readers enjoyed how he was able to grab your attention when you were reading. At times Capote may have been socially awkward, everyone remembers him as a very noteworthy author in American history. The beginning of Capote’s writing career began in his early years where he fell under the supervision of his instructor (Plimpton 470). Although he was very unsuccessful in school, and never attended college, many exams confirmed that he had incredible intellect. Many of his novels showed his intelligence by the way he would describe and lure readers into his stories. His personality was different and it got readers attention. Even as a child, Capote was regarded as â€Å"†¦Prim and proper Lord Faunteroy†¦Incredibly protective of his clothes [and look]† which made many believe is what had caused him to ultimately be publicly gay (Pimpton2). Although nobody knew Capote better then his friend Harper Lee; who actually based the character of Dill in her novel To Kill a Mockingbird on the young Capote (Pimpton 2). Despite the way he may have acted or done things, Truman Capote was nothing less then a mastermind. Many of his novels are remembered and loved by the various techniques used by Capote. He was truly unlike any other person in this world. Intelligent, different, and even socially awkward at times, Truman Capote is one of the most known and remembered authors of the 20th century. How to cite Truman Capote Research, Essay examples

Thursday, December 5, 2019

If it be friendship that you desire, then I am re Essay Example For Students

If it be friendship that you desire, then I am re Essay ady for itbut to be your subject, that I cannot be. As quoted by The famous quote of Chief Machemba, who resisted European conquest along with his tribal community. Throughout the 19th century, the powers of Europe sought control over Africa. The countries like Portugal, Great Britain, France, Belgium, Germany, Spain and Italy were involved in the colonization of Africa for the abundant resources that were available then. At the end of 1912 the only states in Africa that werent colonized were Liberia and Ethiopia. Liberia and Ethiopia were the only countries that werent colonized in the vast African continent. The conquest impacted the daily lives of African people relinquishing their resources. We will write a custom essay on If it be friendship that you desire, then I am re specifically for you for only $16.38 $13.9/page Order now In conclusion, European imperialism in Africa had many negative effects. Africa was devastated by the wrath of the European empires, however the power of these nations stretched around the world. Europeans caused many negative problems in Africa. Many Africans, at that time felt that the Europeans got more out of imperialistic laws than they did, for example many Africans were treated poorly, but most of them were transported to other nations where they were subjugated to slavery with no freedom and separated from families. The Europeans saw themselves as superior over other races and wanted the cultures of these people to assimilate into their superior one, as they believed that the Europeans tried to change the religion, the language and the way of life of the colonized people, which shows how Europeans had little respect for native culture and customs. In addition, the colonial people had no control over their government or their countrys resources. Since, the European countries w ere often in conflict with one another, they stripped their colonies of their resources to fuel their might, which has made many African countries very poor. , In fact, the nominal gdp for all of Africa combined is less than that of Germany They also created division between the African tribes, which we all witnessed in the Rwandan genocide. This happened even decades after they left in the 1980s because the Belgians placed Tutsis in power over the Hutus. The Hutus were angered by the mistreatment, revolted and mass murdered the Tutsis killing about 500 000 to 1 000 000. As more of the Europeans came to Africa, they brought diseases like smallpox with them. The African people werent immune to this disease, which killed many. Also, most of Africa was stripped of its resources. However, in some cases, imperialism benefited the people of Africa. For example, missionaries caught attention of the African people by showing their generosity and their ways of Christianity. They built school s and medical clinics along churches by which the Africans received health benefits as well as but also education. Over 800 different languages approximately known during the 1870s and only 5 common languages were soon spoken by many Africans because of the missionaries who opened schools along with churches. In addition, imperialism also brought jobs and industry to the colonies and it introduced the ideas of constitutional government to the Africans. Imperialism is the total domination of the political, economic, or cultural aspects or a nation. Imperial colonization has been occurringsensethe beginning of time. An imperialistic nation would increase its importance and power by winning an empire. Some takeovers were forced by political rivalries. One nation might seize a territory to prevent a competitor from expanding into that region. Some nations would expand to boost their economic value, or personal wealth. Imperialism advances a countries politics, society, and economic val ue into a powerful money-making country.The political aspect of imperialism progresses a country from beingweekinto a strong fighting nation. For example, when the French were taking over parts of Africa, the communication ofthe two countriesincreased and they started to share the Suez Canal. Also, when the British government set up a system of Colonial rule, it controlled over 280 million Indians. Thus, encouraging officials to learn new languages. When the Spanish took over Latin America they constructed a Council of the Indies which issued over 400,00 orders to improve the cities. However,without society, politics would have gotten nowhere.The social aspect of imperialism was very important. First, by the colonization of countriesscientist could find causes and treatments to diseases such as malaria and yellow fever. Also, Britain built canals, roads, and railways which opened Indias interior. The Spanish improved the Aztecs cities by making public waterways, paved and lighted st reets, and an invention the printing press. The society increased but when it enhanced the economics boosted also.The economics of imperialism is a major reason why nations would take over other countries. InAfricathey introduced better farming techniques like dykes and irrigation canals, which boosted the money growth. The British improved medical care that includeddoctor education, thus leading into a boom in the population. The Spanish exported crops and raw materials, making fortunes for the new government.In conclusion, imperialism is a vehicle of advancement. This promotion is brought to countries that arent strong enough to defendthem selves. In most cases,the economic value of the new country will increase. Therefore,imperialism advances a countries politics, society, and economic value into a powerful money making country. .ue2588bb5a38d60abaaa31c3e2520f5fc , .ue2588bb5a38d60abaaa31c3e2520f5fc .postImageUrl , .ue2588bb5a38d60abaaa31c3e2520f5fc .centered-text-area { min-height: 80px; position: relative; } .ue2588bb5a38d60abaaa31c3e2520f5fc , .ue2588bb5a38d60abaaa31c3e2520f5fc:hover , .ue2588bb5a38d60abaaa31c3e2520f5fc:visited , .ue2588bb5a38d60abaaa31c3e2520f5fc:active { border:0!important; } .ue2588bb5a38d60abaaa31c3e2520f5fc .clearfix:after { content: ""; display: table; clear: both; } .ue2588bb5a38d60abaaa31c3e2520f5fc { display: block; transition: background-color 250ms; webkit-transition: background-color 250ms; width: 100%; opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #95A5A6; } .ue2588bb5a38d60abaaa31c3e2520f5fc:active , .ue2588bb5a38d60abaaa31c3e2520f5fc:hover { opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #2C3E50; } .ue2588bb5a38d60abaaa31c3e2520f5fc .centered-text-area { width: 100%; position: relative ; } .ue2588bb5a38d60abaaa31c3e2520f5fc .ctaText { border-bottom: 0 solid #fff; color: #2980B9; font-size: 16px; font-weight: bold; margin: 0; padding: 0; text-decoration: underline; } .ue2588bb5a38d60abaaa31c3e2520f5fc .postTitle { color: #FFFFFF; font-size: 16px; font-weight: 600; margin: 0; padding: 0; width: 100%; } .ue2588bb5a38d60abaaa31c3e2520f5fc .ctaButton { background-color: #7F8C8D!important; color: #2980B9; border: none; border-radius: 3px; box-shadow: none; font-size: 14px; font-weight: bold; line-height: 26px; moz-border-radius: 3px; text-align: center; text-decoration: none; text-shadow: none; width: 80px; min-height: 80px; background: url(https://artscolumbia.org/wp-content/plugins/intelly-related-posts/assets/images/simple-arrow.png)no-repeat; position: absolute; right: 0; top: 0; } .ue2588bb5a38d60abaaa31c3e2520f5fc:hover .ctaButton { background-color: #34495E!important; } .ue2588bb5a38d60abaaa31c3e2520f5fc .centered-text { display: table; height: 80px; padding-left : 18px; top: 0; } .ue2588bb5a38d60abaaa31c3e2520f5fc .ue2588bb5a38d60abaaa31c3e2520f5fc-content { display: table-cell; margin: 0; padding: 0; padding-right: 108px; position: relative; vertical-align: middle; width: 100%; } .ue2588bb5a38d60abaaa31c3e2520f5fc:after { content: ""; display: block; clear: both; } READ: Christina Harwood Essay INCLUDEPICTURE http://www.planetpapers.com/images/btn-sign-in-full-essay.png * MERGEFORMATINET